A strain of streptococcus equi which can produce hyaluronate capsule has been subjected to metabolic engineering research . and the pathway for its synthesis of hyaluronic acid ( ha ) was systematically studied 透明质酸( hyaluronicacid , ha )是一种重要的粘多糖,改良菌种和选育能产生高分子量ha的高产菌株是发酵法生产工艺的基础。